Branches and ecological states of the gut microbiome: Mapping for future personalized nutritional and therapeutic interventions

A recent study published in Nature Communications1 by researchers from Danone Research (Gif-sur-Yvette) and the University of San Diego in California examined 35,000 fecal samples from different popu...
Published on June 28, 2023 | 1 min read

Fermentation microbiome projects

Here are a list of fermented foods related projects where I am involved:Grand Défi Ferments du Futur Ferments du Futur is a public-private partnership built to accelerate rese...
Published on April 01, 2023 | 1 min read

10 years of research about IBS, gut microbiota and fermented product at Danone Research - what do we found?

Irritable bowel syndrome (IBS) is a common disorder characterized by abdominal pain, bloating, and changes in bowel habits. The role of the gut microbiota in IBS has been increasingly recognized, and several studies have identified alterations in the gut microbial composition and function in I...
Published on January 05, 2023 | 7 min read

Futuristic fermented food for Gut Microbiota

What if we ask an AI to generate a realistic picture about futuristic fermented foods that keep microbiota to stay in an healthy state?This is what I tried with midjourney. Midjourney is a proprietary artificial intelligence program that...
Published on September 30, 2022 | 0 min read

Human gut metatranscriptome changes induced by a fermented milk product are associated with improved tolerance to a flatulogenic diet

In a recent study1, we combined taxonomic, functional, and network analysis from shotgun metatranscriptomics analysis of fecal samples, which were collected during the ingestion of a habitual diet ...
Published on April 08, 2022 | 0 min read

Diet and gut microbiome interactions of relevance for symptoms in irritable bowel syndrome

We published a study entitled “Diet and gut microbiome interactions of relevance for symptoms in irritable bowel syndrome” in Microbiome journal.First, we used a food tree...
Published on March 26, 2021 | 1 min read

Keystone Cork 2019 Microbiome

We presented a study entitled “Gut microbiome hysteresis is associated with durable mucosal alterations” during the Keystone Symposia poster session helded at Killarney : “Microbiome: Therapeutic Implications”<img itemprop="image" src...
Published on October 06, 2019 | 2 min read

Predict the gut microbiota resistome

The intestinal microbiota is considered to be a major reservoir of antibiotic resistance determinants (ARDs) that could potentially be transferred to bacterial pathogens via mobile genetic elements. A collaboration between several research institute including INRA, AP-HP and Institut Pasteur s...
Published on November 27, 2018 | 1 min read

Symptoms severity of irritable bowel syndrome associated with gut microbiota

Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder in western societies, characterized by chronic abdominal pain and discomfort. It affects about 11% of the adult population and strongly impairs quality of life, social function, work productivity and brin...
Published on November 05, 2016 | 2 min read

Gut microbiota richness promotes its stability upon increased dietary fibre intake

A study1 published in Environmental Microbiology in September 2015 showed how gut microbiota stability depend of its richness when individuals took high fibe...
Published on January 29, 2016 | 1 min read

Using gut microbiota to detect colon cancer

A study1 published in Molecular System Biology showed how gut microbiota could be used to detect colon cancer in combination with standard fecal occult blood tes...
Published on November 29, 2014 | 4 min read

Human gut metagenomics, five years of exciting exploration

I defended my PhD in December 2009 and I knew that gut metagenomics will become more and more exiting with such big consortia such as MetaHIT and <a...
Published on July 07, 2014 | 5 min read

Gut Microbiota for Health summit 2014

The Gut Microbiota for Health summit organized byAGA with ENSM took place in Miami, 8-9 March 2014.Scientific exchanges were around the role of gut microbiota in various disease like IBS, IBD and metabolic syndrome l...
Published on March 23, 2014 | 0 min read

What is MetaGenoPolis ?

I’m working since 1 year at Metagenopolis unit at INRA institute. Here is below the presentation video. MetaGenoPolis (MGP) has as strategic goal to demonstrate the impact of the human gut microbiota on health and disease, by making ...
Published on February 13, 2014 | 0 min read

A new metagenomic marker genes method to study microbiota

Numerical ecology analysis of microbiota by metagenomic sequencing, currently depend on the availability of DNA sequences of microbial genomes in the public databases. Often this approach leads to biased interpretation because the majority of the microbial community has no reference genome. To...
Published on October 30, 2013 | 1 min read

Gastric bypass help the crosstalk between microbiota and host adipocytes

Following their <a href="/index.php/actualites/11-actualites-scientifiques/43-microbi...
Published on May 31, 2013 | 0 min read

Mycobacterium tuberculosis origins

In 2006, I worked at Pasteur Institute (Sylvain Brisse groups) on characterization of special smooth strains isolated in Africa1 which seems to be related to M.tuberculosis (known to have a ...
Published on March 27, 2013 | 0 min read

Genomic variation landscape of the human gut microbiome

A joi...
Published on December 14, 2012 | 1 min read

Gut microbiota for Health expert exchange

A new web platform related to gut microbiota field was recently launched. This web platform aims to enhance debate ...
Published on November 12, 2012 | 0 min read

International Human Microbiome Congress Paris 2012

The next International Human Microbiome Congress (IHMC) organized byMetaHIT be held in Paris, 19-21 March 2012, at thePalais Brongniart. This conference is under the patronage of UNESCO andsupported by the European Commission. This is the larges...
Published on February 25, 2012 | 1 min read

my.microbes, an open large-scale human microbiome study

The discoverers of enterotypes launched a large scale project called my.microbes. Since Sept. 8, the project is open to anyone who wants to contribute. The study aims to analyze, through high throughput te...
Published on September 08, 2011 | 1 min read

Commensal gut bacteria and immune modulation

After the development of a cell reporter system for NF-kB pathway and identification of new potential therapeutic molecule by metagenomic screening, INRA scientists have focused directly on intestinal bacteria isolated in the laboratory. The ability to modulate the NF-kB pathway, central for i...
Published on May 01, 2011 | 1 min read

Human gut microbiome and enterotypes

A joint effort between scientists from EMBL (Heidelberg, Germany) and the others partners from the European MetaHIT project have permit to describe that Humans can be split in different group based on their gut microbiota composition. Those groups, named en...
Published on April 20, 2011 | 1 min read

A decades of metagenomics approach based studies, a text mining overview

The microbiota is the sum of microbial element of a given ecosystem which can be ocean, soils or human body site like oral and gut. In the 90’s, scientist studied microbiota using classical microbiology culture-dependent approach. However, the majority of microbes aren’t cultivable yet and...
Published on April 19, 2011 | 5 min read

Functional metagenomics

Functional metagenomic appears to be totally complementary to the conventional Shotgun metagenomics approach that uses only metagenomics high throughput sequencing to access the biodiversity of an ecosystem. Two studies (Publications) have used thi...
Published on August 16, 2010 | 1 min read